Kentaro Kitadate, D.V.M.

Head-and-shoulders portrait of man in dark suit, striped tie, brick wall and shrubs behind

President, Amino Up Co., Ltd.

Education

  • DVM, Rakuno Gakuen University, Department of Veterinary Medicine

Research Interests

Mr. Kitadate worked as a practicing veterinarian and developed a strong interest in immunology, infectious diseases, oncology, and nutrition. At Amino Up Co., Ltd., he has been involved in clinical development activities for both human and veterinary applications.

Selected Publications

  1. Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells. Tomoko Koda, Jun Takanari, Kentaro Kitadate, Hideki Imai. Natural Product Communications, 12(10): 1631-1633 (2017).
  2. Perilla leaf extract prevents atopic dermatitis induced by an extract of Dermatophagoides farinae in NC/Nga mice. Ken-Ichi Komatsu, Jun Takanari, Takahiro Maeda, Kentaro Kitadate, Takashi Sato, Yoshihiro Mihara, Kaori Uehara, Koji Wakame. Asian Pacific Journal of Allergy and Immunology, 34(4): 272-277 (2016). [PubMed]
  3. Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea. Kentaro Kitadate, Kohei Homma, Ashley Roberts, Takahiro Maeda. Regulatory Toxicology and Pharmacology, 68(1): 140-146 (2014). [PubMed]
  4. ETAS, an enzyme-treated asparagus extract, attenuates amyloid beta-induced cellular disorder in PC12 cells. Junetsu Ogasawara, Tomohiro Ito, Koji Wakame, Kentaro Kitadate, Takuya Sakurai, Shogo Sato, Yoshinaga Ishibashi, Tetsuya Izawa, Kazuto Takahashi, Hitoshi Ishida, Ichiro Takabatake, Takako Kizaki, Hideki Ohno. Natural Product Communications, 9(4): 561-564 (2014). [PubMed]
  5. Enzyme-treated Asparagus officinalis extract shows neuroprotective effects and attenuates cognitive impairment in senescence-accelerated mice. Takuya Sakurai, Tomohiro Ito, Koji Wakame, Kentaro Kitadate, Takashi Arai, Junetsu Ogasawara, Takako Kizaki, Shogo Sato, Yoshinaga Ishibashi, Tomonori Fujiwara, Kimio Akagawa, Hitoshi Ishida, Hideki Ohno. Natural Product Communications, 9(1): 101-106 (2014). [PubMed]
  6. Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells. Takuya Sakurai, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Junetsu Ogasawara, Takako Kizaki, Shogo Sato, Tomonori Fujiwara, Kimio Akagawa, Tetsuya Izawa, Hideki Ohno. British Journal of Nutrition, 110(9): 1549-1558 (2013). [PubMed]
  7. Oligonol-induced degradation of perilipin 1 is regulated through lysosomal degradation machinery. Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Takuya Sakurai, Takako Kizaki, Tetsuya Izawa, Hitoshi Ishida, Hideki Ohno. Natural Product Communications, 7(9): 1193-1196 (2012). [PubMed]
  8. Comparison of the effect of oligonol, a new lychee fruit-derived low molecular form of polyphenol, and epigallocatechin-3-gallate on lipolysis in rat primary adipocytes. Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Takuya Sakurai, Takako Kizaki, Tetsuya Izawa, Hitoshi Ishida, Hideki Ohno. Phytotherapy Research, 25(3): 467-471 (2011). [PubMed]
  9. Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/Raf-1/MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes. Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Takuya Sakurai, Takako Kizaki, Tetsuya Izawa, Hitoshi Ishida, Masataka Tanno, Hideki Ohno. Biochemical and Biophysical Research Communications, 402(3): 554-559 (2010). [PubMed]
  10. Oligomerized grape seed polyphenols attenuate inflammatory changes due to antioxidative properties in coculture of adipocytes and macrophages. Takuya Sakurai, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Takako Kizaki, Yasumasa Kondoh, Tetsuya Izawa, Hitoshi Ishida, Zsolt Radák, Hideki Ohno. Journal of Nutritional Biochemistry, 21(1): 47-54 (2010). [PubMed]
  11. Oligonol, a new lychee fruit-derived low-molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway. Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii, Takuya Sakurai, Takako Kizaki, Tetsuya Izawa, Hitoshi Ishida, Hideki Ohno. Phytotherapy Research, 23: 1626-1633 (2009). [PubMed]
  12. The Function of the Next Generation of Polyphenol "Oligonol" [Article in Japanese]. Takehito Miura, Kentaro Kitadate. Japanese Journal of Complementary and Alternative Medicine, 5(3): 163-171 (2008).
  13. The supplementation of oligonol, the new lychee fruit-derived polyphenol converting into a low-molecular form, has a positive effect on fatigue during regular track-and-field training in young athletes. Hideki Ohno, Takuya Sakurai, Tatsuya Hisajima, Shigeru Abe, Takako Kizaki, Jun-etsu Ogasawara, Yoshinaga Ishibashi, Kazuhiko Imaizumi, Tohru Takemasa, Shukoh Haga, Kentaro Kitadate, Hiroshi Nishioka, Hajime Fujii. Advances in Exercise and Sports Physiology, 13(4): 93-99 (2008).
  14. Protective Effects of Buckwheat Hull Extract against Experimental Hippocampus Injury Induced by Trimethyltin in Rats [Article in Japanese]. Tomoko Koda, Yoshiki Kuroda, Yasuhiro Ueno, Kentaro Kitadate, Hideki Imai. Japanese Journal of Hygiene, 63: 711-716 (2008). [PubMed]