Postdoctoral Researcher Office: 3150A Meyer / 530-752-3548 Lab: 3407 Meyer / 530-752-2639 Email:lactisgoretta@ucdavis.edu

M.S., Biochemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina Dr. Actis-Goretta's research area focuses on the elucidation of molecular and cellular mechanisms underlying the putative beneficial effects of flavanols and flavanol-rich foods on degenerative human diseases such as cardiovascular disorders and cancer.

Fraga CG, Actis-Goretta L, Ottaviani JI, Carrasquedo F, Lotito SB, Lazarus S, Schmitz HH, Keen CL. Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players. Clin Dev Immunol. 2005 Mar;12(1):11-7. Actis-Goretta L, Carrasquedo F, Fraga CG. The regular supplementation with an antioxidant mixture decreases oxidative stress in healthy humans. Gender effect. Clin Chim Acta. 2004 Nov;349(1-2):97-103. Actis-Goretta L, Ottaviani JI, Keen CL, Fraga CG. Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins.FEBS Lett. 2003 Dec 18;555(3):597-600. Actis-Goretta L, Mackenzie GG, Oteiza PI, Fraga CG. Comparative study on the antioxidant capacity of wines and other plant-derived beverages. Ann N Y Acad Sci. 2002 May;957:279-83. Valdez LB, Actis-Goretta L, Boveris A. Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite. Ann N Y Acad Sci. 2002 May;957:274-8. Alvarez S, Zaobornyj T, Actis-Goretta L, Fraga CG, Boveris A. Polyphenols and red wine as peroxynitrite scavengers: a chemiluminescent assay. Ann N Y Acad Sci. 2002 May;957:271-3. Lotito SB, Actis-Goretta L, Renart ML, Caligiuri M, Rein D, Schmitz HH, Steinberg FM, Keen CL, Fraga CG. Influence of oligomer chain length on the antioxidant activity of procyanidins. Biochem Biophys Res Commun. 2000 Oct 5;276(3):945-51.