Javier Ottaviani, Ph.D.

 Javier  Ottaviani, Ph.D.

Position

  • Associate
  • Agricultural Experiment Station

Position

  • Manager of MARS CoreLab at UC Davis
  • MARS, Incorporated

Contact

Education

  • Ph.D., Biochemistry, University of Buenos Aires, Argentina

Research Interests

Dr. Ottaviani studies the putative beneficial effects of plant-derived polyphenolic compounds against degenerative disorders, with an emphasis on vascular disease.

Selected Publications

Ottaviani JI, Balz M, Kimball J, Ensunsa JL, Fong R, Momma TY, Kwik-Uribe C, Schroeter H, Keen CL. Safety and efficacy of cocoa flavanol intake in healthy adults: a randomized, controlled, double-masked trial. Am J Clin Nutr. 2015 Nov 4. pii: ajcn116178. [PubMed]

Actis-Goretta L, Ottaviani, JI and Fraga CG. Inhibition of angiotensin converting enzyme by flavonoid-rich-food. To be sent to J Agric Food Chem. [PubMed]

Ottaviani, JI, Fraga CG. Modulation of ACE activity by zinc. In preparation to be sent to Arch. Biochem. Biophys.

Ottaviani, JI, Actis-Goretta L, Fraga CG. Procyanidins prevent angiotensin I hydrolysis through ACE inhibition. To be send for publication to Arch. Biochem. Biophys.

Fraga CG, Actis-Goretta L, Carrasquedo F, Lotito SB, Ottaviani JI, Lazarus SA, Schmitz HH, Keen CL. Regular consumption of a flavonoid-rich chocolate improved markers of cardiovascular health and oxidant stress in young soccer players. Clin. Develop. Immunol. (in press) [PubMed]

Actis-Goretta L, Ottaviani JI, , Keen CL, Fraga CG. Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins. FEBS Lett 2003, 555: 597-600. [PubMed]

Ottaviani JI, Carrasquedo F, Keen CL, Lazarus SA, Schmitz HH, Fraga CG. Influence of cocoa-derived flavanols and procyanidins on UV-C mediated formation of 8-oxo-7,8-dehydro-2'-deoxyguanosine in isolated DNA. Arch Biochem Biophys 2002, 406: 203-208. [PubMed]