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Angela M. Zivkovic

Angela M. Zivkovic

  • Assistant Professor, Nutrition Department
  • Assistant Nutritionist in Agricultural Experiment Station

3245 Meyer

(530) 574-9043



  • B.S., Conservation & Resource Studies, University of, California Berkeley
  • Ph.D., Nutritional Biology, University of California, Davis

Research Interests

Dr. Zivkovic’s research program focuses on the development of assessment tools and dietary strategies to personalize health. Dr. Zivkovic is particularly interested in assessing the effects of diet and dietary constituents on lipid metabolism, lipoprotein composition and function, inflammation, and the establishment and maintenance of a healthy gut microbiome. Dr. Zivkovic’s group integrates clinical, metabolomic, glycomic, transcriptomic, and genomic approaches to characterize metabolic phenotypes and their responsiveness to different diets. Research projects are both domestic and international in scope.

Selected Publications

  • Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res 2013;57(8):1319-35. [PubMed]
  • Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One 2013;8(10):e76575. [PubMed]
  • Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations. Metabolomics 2012;8(6):1102-13. [PubMed]
  • Totten SM, Zivkovic AM, Wu S, Ngyuen U, Freeman SL, Ruhaak LR, Darboe MK, German JB, Prentice AM, Lebrilla CB. Comprehensive profiles of human milk oligosaccharides yield highly sensitive and specific markers for determining secretor status in lactating mothers. J Proteome Res 2012;11(12):6124-33. [PubMed]
  • Nwosu CC, Aldredge DL, Lee H, Lerno LA, Zivkovic AM, German JB, Lebrilla CB. Comparison of the human and bovine milk N-glycome via high-performance microfluidic chip liquid chromatography and tandem mass spectrometry. J Proteome Res 2012;11(5):2912-24. [PubMed]
  • Hua S, Nwosu CC, Strum JS, Seipert RR, An HJ, Zivkovic AM, German JB, Lebrilla CB. Site-specific protein glycosylation analysis with glycan isomer differentiation. Anal Bioanal Chem 2012;403(5):1291-302. [PubMed]
  • Zivkovic AM, German JB, Lebrilla CB, Mills DA. Human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proc Natl Acad Sci U S A 2011;108 Suppl 1:4653-8. [PubMed]
  • Zivkovic AM, Barile D. Bovine milk as a source of functional oligosaccharides for improving human health. Adv Nutr 2011;2(3):284-9. [PubMed]
  • Nwosu CC, Seipert RR, Strum JS, Hua SS, An HJ, Zivkovic AM, German BJ, Lebrilla CB. Simultaneous and extensive site-specific N- and O-glycosylation analysis in protein mixtures. J Proteome Res 2011;10(5):2612-24. [PubMed]
  • German JB, Zivkovic AM, Dallas DC, Smilowitz JT. Nutrigenomics and personalized diets: What will they mean for food? Annu Rev Food Sci Technol 2011;2:97-123. [PubMed]
  • Froehlich JW, Barboza M, Chu C, Lerno LA, Jr., Clowers BH, Zivkovic AM, German JB, Lebrilla CB. Nano-LC-MS/MS of glycopeptides produced by nonspecific proteolysis enables rapid and extensive site-specific glycosylation determination. Anal Chem 2011;83(14):5541-7. [PubMed]
  • Dallas DC, Martin WF, Strum JS, Zivkovic AM, Smilowitz JT, Underwood MA, Affolter M, Lebrilla CB, German JB. N-linked glycan profiling of mature human milk by high-performance microfluidic chip liquid chromatography time-of-flight tandem mass spectrometry. J Agric Food Chem 2011;59(8):4255-63. [PubMed]
  • Bricarello DA, Smilowitz JT, Zivkovic AM, German JB, Parikh AN. Reconstituted lipoprotein: a versatile class of biologically-inspired nanostructures. ACS Nano 2011;5(1):42-57. [PubMed]
  • Smilowitz JT, German JB, Zivkovic AM. Food Intake and Obesity: The Case of Fat in "Fat Detection: Taste, Texture, and Post Ingestive Effects" Boca Raton FL: Taylor & Francis Group, LLC, 2010. [PubMed]
  • Argov-Argaman N, Smilowitz JT, Bricarello DA, Barboza M, Lerno L, Froehlich JW, Lee H, Zivkovic AM, Lemay DG, Freeman S, Lebrilla CB, Parikh AN, German JB. Lactosomes: Structural and Compositional Classification of Unique Nanometer-Sized Protein Lipid Particles of Human Milk. J Agric Food Chem 2010. [PubMed]
  • Zivkovic AM, Wiest MM, Nguyen UT, Davis R, Watkins SM, German JB. Effects of sample handling and storage on quantitative lipid analysis in human serum. Metabolomics 2009;5(4):507-16. [PubMed]
  • Zivkovic AM, Wiest MM, Nguyen U, Nording ML, Watkins SM, German JB. Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach. Metabolomics 2009;5(2):209-18. [PubMed]
  • Zivkovic AM, German JB. Metabolomics for assessment of nutritional status. Curr Opin Clin Nutr Metab Care 2009;12(5):501-7. [PubMed]
  • Zivkovic AM, Bruce German J, Esfandiari F, Halsted CH. Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. Alcohol Clin Exp Res 2009;33(4):751-8. [PubMed]
  • Zivkovic AM, German JB, Sanyal AJ. Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease. Am J Clin Nutr 2007;86(2):285-300. [PubMed]
  • Zivkovic AM, German JB. Individual variation in the metabolic syndrome: a new perspective on the debate. Am J Clin Nutr 2007;85(1):240-1; author reply 1-2. [PubMed]
  • Lemay DG, Zivkovic AM, German JB. Building the bridges to bioinformatics in nutrition research. Am J Clin Nutr 2007;86(5):1261-9. [PubMed]
  • German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM. Lipidomics and lipid profiling in metabolomics. Curr Opin Lipidol 2007;18(1):66-71. [PubMed]
  • German JB, Smilowitz JT, Zivkovic AM. Lipoproteins: When size really matters. Curr Opin Colloid Interface Sci 2006;11(2-3):171-83. [PubMed]