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Gertrud Schuster

Gertrud Schuster

  • Assistant Project Scientist, Department of Nutrition


(530) 752-1351



  • Ph.D., Technical University Munich, Germany
  • MS (Diploma) in Biomedicine (Human Biology), Philipps-University at Marburg, Germany

Research Interests

Dr Schuster’s research interest is directed towards the effects of nutrients on lipid metabolism and immune response. Her main focus is to investigate the effects of fat-solulable vitamins, fatty acids, or cholesterol metabolites on gene expression, which is mediated by nuclear receptors (like RXR, RAR, LXR or PPAR).

Selected Publications

  • Knecht, W., Altekruse, D., Schuster, G.U., Günnewig, K. and Löffler, M. Investigation of Mammalian Dihydroorotate-Dehydrogenase: Topochemical Relation to the Respiratory Chain. Biol Chem Hoppe Seyler, 1994, 375, 64.
  • Löffler, M., Rotgeri, A., Becker, C., Lakaschus, G. and Schuster, G.U. Dihydroorotate dehydrogenase from rat liver: localization, characterization and sequencing cDNA clones. German Journal of Gastroenterology, 1994, 32, 53.
  • Löffler, M., Becker, C., Wegerle E. and Schuster G.U. Catalytic enzyme histochemistry and biochemical analysis of dihydroorotate dehydrogenase/ oxidase and succinat dehydrogenase in mammalian tissues, cells and mitochondria. Histochem. Cell Biol., 1996, 105, 119-128.
  • Löffler, M., Jöckel, J., Schuster G.U. and Becker C. Dihydroorotate: ubiquinone oxidoreductasse links mitochondria in the biosynthesis of pyrimidine nucleotides.Mol. Cell Biochem. 1997, 174, 125-129.
  • Peters, H., Schuster, G.U., Neubüser, A., Richter, T., Höfler, H. and Balling, R. Isolation of the PAX9 cDNA from adult human esophagus. Mamm. Genome, 1997, 8, 62-64.
  • Alberti, S., Schuster, G.U., Parini, P., Feltkamp, D., Diczfalusy, U., Rudling, M., Angelin, B., Björkhem, I., Pettersson, S. and Gustafsson, J. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRb-deficient mice. J. Clin. Invest, 2001, 107, 565-573.
  • Tobin, K.A.R., Ulven, S.M., Schuster, G.U., Steineger, H.H., Andresen, S.M., Gustafsson, J. and Nebb, H.I. LXRs as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J. Biol. Chem., 2002, 277, 10691-10697.
  • Steffensen, K.R., Schuster, G.U., Parini, P., Holter, E., Sadek, C.M., Cassel, T., Eskild, W. and Gustafsson, J. Different regulation of the LXRa promoter activity by isoforms of CCAAT/enhancer-binding proteins. Biochem. Biophys. Res. Commun. 2002; 293:1333-1340.
  • Li-Hawkins, J., Gåvels, M., Olin, M., Lund, E.G., Andersson, U., Schuster, G.U., Björkhem, I., Russell, D.W. and Eggertsen, G. Cholic acid mediates negative feedback regulation of bile acid synthesis in mice. J. Clin. Invest. 2002;110:1191-1200.
  • Stulnig, T.M., Steffensen, K.R., Gao, H., Reimers, M., Dahlman-Wright, K., Schuster, G.U. and Gustafsson, J. Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue. Mol. Pharmacol. 2002;62:1299-1305.
  • Stulnig T.M., Oppermann, U., Steffensen, K.R., Schuster, G.U. and Gustafsson, J. Liver X Receptors downregulate 11b-hydroxysteroid dehydrogenase type 1 expression and activity. Diabetes, 2002;51:2426-33.
  • Wang, L., Schuster, G.U., Hultenby, K., Zhang, Q., Andersson, S. and Gustafsson, J. Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration.Proc Natl Acad Sci U.S.A., 2002;99:13878-13883.
  • Schuster, G.U., Parini, P., Wang, L., Alberti, S., Steffensen, K.R., Hansson, G.K., Angelin, B. and Gustafsson, J. Accumulation of foam cells in LXR-deficient mice. Circulation, 2002;106:1147-53.
  • Juvet, L.K., Andresen, S.M., Schuster, G.U., Dalen, K.T., Tobin, K.A.R., Hollung, K., Haugen, F., Jacinto, S., Ulven, S. M., Bamberg, K., Gustafsson, J.Å. and Nebb, H.I. On the role of LXR-alpha in lipid accumulation in adipocytes. Mol Endo, 2002;17:172-182.
  • Antonson, P., Schuster, G.U., Wang, L., Rozell, B., Holter, E., Flodby, P., Treuter, E., Holmgren, L. and Gustafsson J. Inactivation of the nuclear receptor coactivator RAP 250 in mice results in placental vascular dysfunction. Mol. Cell. Biol., 2003;23:1260-1268.
  • Steffensen, K. R., Nilsson, M., Schuster, G.U., Stulnig, T.M., Dahlman-Wright, K. and Gustafsson J. Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of Liver X Receptors alpha and beta respectively. Biochem. Biophys. Res. Commun. 2003;310:589-593.