UCDavis University of California

Education

• B.A., Natural Sciences, Johns Hopkins University
• M.S., Biology & Nutrition, Pennsylvania State University
• Ph.D., Nutrition, University of California, Davis

Research Interests

Dr. Hackman’s research addresses the role of nutritional and botanical supplements for health enhancement. He is currently studying the role of nuts and flavanol-rich botanical extracts on vascular function and inflammation, and the role of mushroom and soy extracts in prostate cancer.

Selected Publications

• Hackman RM, Wagner EL. The Senior Gardening and Nutrition Project: Development and transport of a dietary behavior change and health promotion program. Journal of Nutrition Education 1990;22: 262-270.
• Hackman RM. Nutrition and sports performance for the older athlete. In: Sports Science Symposium: Proceedings from the VIIIth World Veterans' championships. E. Zemper, G. Steigelman and S. James (Eds.) International Institute for Sports and Human Performance, Eugene, pp. 77-85, 1991.
• Hackman RM, Ellis BK Increases in lean body mass and loss of fat mass among moderately obese women in a comprehensive weight management program. International Clinical Nutrition Reviews 1991;11:184-189.
• Hackman RM, Katra J, Geertsen S. The athletic trainer's role in modifying nutritional behaviors of adolescent athletes: Putting theory into practice. Journal of Athletic Training 1992;27:262-267.
• Hackman RM, Ellis BK, Brown, RL. Phosphorus magnetic resonance spectra and changes in body composition during weight loss. Journal of the American College of Nutrition 1994;13:243-250.
• Hackman RM, Ellis BK, Brown, RL. Phosphorus magnetic resonance spectra and changes in body composition during weight loss. Journal of the American College of Nutrition 1994;13:243-250.
• Hackman RM, Oman R, Brown RL. Cellular bioenergetics, work performance, body composition and psychological indices among women in a diet-exercise program. Nutrition Research 1995;15:455-465.
• Hackman, R.M., Stern, J.S., and Gershwin, M.E. Complementary and alternative medicine and asthma. Clinical Reviews in Allergy and Immunology 1996;14:321-37.
• Borchers, A.T., Hackman, R.M., Keen, C.L., Stern, J.S., and Gershwin, M.E. Complementary medicine: A review of immunomodulatory effects of Chinese herbal medicines. American Journal of Clinical Nutrition 1997;66:1303-12.
• Davis, P.A., Gold, E.B., Hackman, R.M., Stern, J.S. and Gershwin, M.E. The use of complementary/alternative medicine for the treatment of asthma in the United States. Investigative Allergology and Clinical Immunology 1998;8:73-77.
• Davis, P.A., Chang, C., Hackman, R.M., Stern, J.S., and Gershwin, M.E. Acupuncture in the treatment of asthma: A critical review. Allergology and Immunopathology 1998;26:263-71.
• Borchers, A.T., Van de Water, J., Kenny, T.P., Keen, C.L., Stern, J.S., Hackman, R.M., and Gershwin, M.E. The comparative effects of three species of ginseng on human peripheral blood lymphocyte proliferative responses. International Journal of Immunotherapy 1998;14:143-52.
• Henderson, G.L., Harkey, M.R., Gershwin, M.E., Hackman, R.M., Stern, J.S., and Stresser, D.M. Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity. Life Sciences 1999;65:209-14.
• Mao, T., Van de Water, J., Keen, C.L., Stern, J.S., Hackman, R.M., and Gershwin, M.E. Two mushrooms, Grifola frondosa and Ganoderma lucidum, can stimulate cytokine gene expression and proliferation in human T lymphocytes. International Journal of Immunotherapy 1999;15:13-22.
• Borchers A.T., Stern, J.S., Hackman, R.M., Keen, C.L., and Gershwin, M.E. Mushrooms, tumors, and immunity. Proceedings of the Society for Experimental Biology and Medicine 1999;221:281-93.
• Hackman, R.M., Stern, J.S., and Gershwin, M.E. Complementary/alternative therapies in general medicine: Asthma and allergies. In: Complementary/Alternative Medicine: An Evidence-Based Approach, J.W. Spencer and J.J. Jacobs (Eds.). Mosby Year Book, St. Louis, Chapter 3, pp. 65-89, 1999.
• Hackman, R.M., Stern, J.S., and Gershwin, M.E. Hypnosis and asthma: A critical review. Journal of Asthma 2000;37:1-15.
• Harkey, M.R., Henderson, G.L., Gershwin, M.E., Stern, J.S. and Hackman, R.M. Variability of commercial ginseng products: an analysis of 25 preparations. American Journal of Clinical Nutrition 2001;73:1101-6.
• Ji, Q.L., Harkey, M.R., Henderson, G.L., Gershwin, M.E., Stern, J.S. and Hackman, R.M. Quantitative determination of ginsenosides by high performance liquid chromatography-tandem mass spectrometry. Phytochemical Analysis 2001;12:320-6.
• deVere White, R.W., Hackman, R.M., Soares, S.E., Beckett, L.A., and Sun, B. Effects of a mushroom mycelium extract on the treatment of prostate cancer. Urology 60:640-4, 2002.
• Zhu, Q.Y., Hackman, R.M., Ensunsa, J.L., Holt, R.R. and Keen, C.L. Antioxidative activities of oolong tea. Journal of Agricultural and Food Chemistry 50:6929-34, 2002.
• Schock, B.C., Koostra, J., Kwack, S., Hackman, R.M., van der Vliet, A. and Cross, C.E. Ascorbic acid in nasal and tracheobronchial airway lining fluids. Free Radical Biology and Medicine 37:1393-1401, 2004.
• deVere White, R.W., Hackman, R.M., Soares, S.E., Beckett, L.A., Li, Y. and Sun, B. Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer. Urology 63:259-63, 2004.
• Ray, S., Patel, C., Phadke, S., Hackman, R.M. and Stohs, S. Short-term or long-term in vivo exposure to an ephedra and caffeine containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice. Archives of Toxicology 79:330-340, 2005.
• Hackman, R.M., Havel, P.J., Schwartz, H.J., Rutledge, J.C., Watnik, M.R., Noceti, E.M., Stohs, S.J., Stern, J.S., and Keen, C.L. Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: A randomized controlled trial. International Journal of Obesity 30:1545-56, 2006.
• Hackman, R.M., Polagruto, J.A., Zhu, Q.Y., Kosuna, K., Sun, B., Fujii, H. and Keen, C.L. Flavanols: Digestion, Absorption and Bioactivity. Phytochemistry Reviews first published online August 29, 2007.
• Polagruto, J.A., Gross, H.B., Kamangar, F., Kosuna, K., Sun, B., Fujii, H., Keen, C.L. and Hackman, R.M. Platelet reactivity in male smokers following the acute consumption of a flavanol-rich grapeseed extract. Journal of Medicinal Food 10:725-30, 2007.
• Hackman, R.M., Polagruto, J.A., Zhu, Q.Y., Kosuna, K., Sun, B., Fujii, H. and Keen, C.L. Flavanols: Digestion, Absorption and Bioactivity. Phytochemistry Reviews 7:195-208, 2008.
• Ray, S.D., Parmar, M., Ismail, S., Rathod, J., Zinkovsky, D., Bulku, E., Gigllioti, J., Hackman, R.M. and Stohs, S.J. Long term exposure effect of a unique metabolic nutrition system containing a diverse group of phytochemicals on serum chemistry and genomic and non-genomic changes in the liver of female B6C3F1 mice. Phytotherapy Research 22:458-71, 2008.
• Hackman, R.M., Kalgaonkar, S., Gross, H.B., Keen, C.L., Fujii, H and Dubick, M.A. Absorption of flavanols from a novel lychee fruit extract rich in flavonoids, and effects on membrane stability and oxidant defense in experimental animals and healthy human adults. Polyphenol Communications 2:837-8, 2008.
• Kalgaonkar, S., Nishioka, H., Gross, H.B., Fujii H., Keen, C.L., and Hackman, R.M. Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and indices of metabolic syndrome in animal models. Phytotherapy Research 24:1223-8, 2010.
• deVere White, R. W., Tsodikov, A., Stapp, E. C., Soares, S. E., Fujii, H., and Hackman, R. M. Effects of an aglycone-rich soy extract on serum isoflavone concentrations and prostate specific antigen in men with localized prostate cancer. Nutrition and Cancer 62: 1036-43, 2010.
• deVere White, R. W., Hackman, R. M., and Kugelmass, J. The dogmas of nutrition and cancer: Time for a second (and maybe third) look. Annals of the New York Academy of Sciences 1190:118-25, 2010.