Dr. Burton-Freeman’s research follows two main themes: 1) Appetite and obesity management and, 2) Vascular disease. Research emphasizes the effects of bioactive food components on mechanistic and behavioral processes of food intake and body weight regulation. Properties of fibers, micro- and macro- molecule interactions, and food matrix effects in the gut to alter metabolic and endocrine systems are a primary focus. Effects of dietary constituents on vascular disease include evaluation of endothelium function, platelet activation, and inflammatory and oxidative stress responses during acute and chronic interventions. The research approach includes human and basic science methodology.